Lymphatic Absorption of Seal and Fish Eicosanoid Production in Rats

llnsaturatedlmonounsaturatedlsaturated fatt)' acids and n-6/n-3 polyunsaturated fatty acids ratios were fed to rats for 3 weeks. Seal oil more effective]y reduced plasma and liyer triglyceride than fish oil. Ratio of the productions of aortic prostacyclin and platelet thromboxane A2 stimulated by thrombin was significantly higher in rats fed sea] oil than in those fed fish oil. The results suggested that the diffl rent intramolecular distribution of EPA and DHA in dietary fat affected tipid metabolism differently in rats.